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Dr Helen Pearson


  • Postdoctoral, Research (Cell Cycle and Cancer Genetics), Peter MacCallum Cancer Institute


Throughout her degree in Biochemistry Dr Pearson developed an interest in cell signalling and the molecular genetics of cancer biology. To this end, she undertook a summer studentship assisting a breast cancer clinical trial which attracted me further towards the field of cancer research. Subsequently, she secured a PhD position at Cardiff University with Prof Alan Clarke where she developed and characterised novel models of prostate cancer. During this research Dr Pearson became fascinated with the molecular mechanisms that predispose prostate cancer, which led her to undertake a postdoctoral position with Dr Patrick Humbert investigating the role of the polarity regulators and prostate cancer.

Current areas of collaboration:

  • Investigating the role of polarity regulators in human prostate (tissue microarray analysis) together with Dr. Ronald Simon, University of Hamburg, Eppendorf, Germany.
  • Investigating the role of APC and Stat3 activation in prostate cancer (in vivo) together with Dr Toby Phesse and Prof. Matthias Ernst, Ludwig Institute for Cancer Research, Melbourne.
  • Investigating the role of PIK3CA in prostate cancer (in vivo) together with Dr Wayne Phillips, Peter MacCallum Cancer Centre, Melbourne.
  • Ras signalling, Scribble, cancer initiation, cancer progression, cell polarity, chemoprevention, endogenous factors, exogenous factors, genes/genetic polymorphisms, marker discovery, metastases, oncogenes and tumour suppressor genes, prostate cancer transgenic models, scientific model systems, technology development.

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