Dr Amy Anne Lubik
Position:
- Post-Doc, The Vancouver Prostate Centre
Credentials:
- Doctor of Philosophy at QUT
Websites:
Biography:
Dr Lubik studied biochemistry / molecular biology at Simon Fraser University in British Columbia, Canada, finishing in 2006 with Honours in HIV research, and a co-operative education certificate, having worked multiple semesters at the Vancouver Prostate Centre, and Merck Frosst Paramedical in Quebec, Canada. While attending University, she was heavily involved in the Red Cross Club, Doctors without Borders, and was president of the swing-dancing club.Following her honours project, she travelled to Ternopol, Ukraine, to teach HIV education in high schools and Universities.
Dr Lubik completed her PhD in 2011 at Queensland University of Technology, Brisbane, Australia. During her PhD, she chaired the QUT Movement for Universities Allied for Essential Medicines, and had an internship in neglected disease patent law with Cambia at QUT. Her thesis focused on insulin and IGF2 and their effects on prostate cancer progression. Her work has largely been interwoven with the Vancouver Prostate Centre and the Australian-Canadian Prostate Cancer Research Alliance.
Dr Lubik continues to be interested in metabolism and prostate cancer; however, her current work for which she has earned a US Department for Defense Trainee Award focuses on a) the epithelial-stromal interactions that contribute to steroidogenesis to further prostate cancer and drug resistance, in both the local prostate and bone microenvironment; b) prostate cancer stem cell contributions to disease.
She also volunteers with many social justice related causes, including her local chapter of Amnesty International.
Best publications:
Key Publications:
-
The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer. Gunter JH, Lubik AA, McKenzie I, Pollak M, Nelson CC. Adv Urol. 2012
- The interactions between insulin and androgens in progression to castrate resistant prostate cancer. Jennifer H Gunter, Amy A Lubik, Ian McKenzie, Michael Pollak, Colleen C Nelson. Advances in Urology. 2012
- IGF2 increases de novo steroidogenesis in prostate cancer cells. Lubik AA, Gunter JH, Hollier BG, Ettinger S, Fazli L, Stylianou N, Hendy SC, Adomat HH, Gleave ME, Pollak M, Herington A, Nelson CC. Endocr Relat Cancer. 2013 Mar 22;20(2):173-86.
- Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer. Seim I, Lubik AA, Lehman ML, Tomlinson N, Whiteside EJ, Herington AC, Nelson CC, Chopin LK. J Mol Endocrinol. 2013 Feb 15;50(2):179-91.
- Insulin directly increases de novo steroidogenesis in prostate cancer cells. Amy A Lubik, Jennifer H Gunter, Stephen C Hendy, Jennifer A Locke, Hans H Adomat, Vanessa Thompson, Emma S Guns, Michael Pollak, Adrian Herington, Martin E Gleave, Vanessa Thompson, and Colleen C. Nelson. Cancer Research. 2011 Sep 1;71(17):5754-64.
- Shirly Sieh, Amy A. Lubik, Judith A. Clements, Colleen C. Nelson and Dietmar W. Hutmacher. Interactions between human osteoblasts and prostate cancer cells in a novel 3D in vitro model. Organogenesis (2010). 6(3): 181-188.
- Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, Ettinger SL, Gleave ME, Nelson CC. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res. (2008). 68(15):6407-15.
IGF-2, androgen action, androgen independence, insulin, metabolic syndrome, normal functioning, steroidogenesis, vaccines.
