Dr Andrew Trotta
Position:
- Dr., Medicine, University of Adelaide, University of Adelaide
Credentials:
- PhD at University of Adelaide
Biography:
Dr Trotta completed his undergraduate degree in Molecular Biology at The University of Adelaide in 2004, and his Honours degree from the Department of Obstetrics and Gyanecoloy in 2005.
He started a PhD in prostate cancer within the Department of Medicine in 2008 under the supervision of Dr Grant Buchanan and Professors Wayne Tilley, Gary Wittert, and Villis Marshall. His research focused on the role that tetratricopeptide repeat containing co-chaperone proteins play in regulating androgen receptor function. He completed his PhD studies in 2011.
Dr Trotta is currently a Postdoctoral research officer within Dr Buchanan's laboratory at the Basil Hetzel Institute and is focusing on identifying extracellular matrix and focal adhesion proteins that change with androgen regulation and cancer progression.
Best publications:
1. Trotta AP, Need EF, Selth LA, Chopra S, Pinnock CB, Leach DA, Coetzee GA, Butler LM, Tilley WD, Buchanan G. Knockdown of the co-chaperone SGTA results in the suppression of androgen and PI3K/AKT signaling and inhibition of prostate cancer cell proliferation. International Journal of Cancer. Accepted May 2013.
2. Trotta AP, Need EF, Butler LM, Selth LA, O'Loughlin MA, Coetzee GA, Tilley WD, Buchanan G. Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client. J Mol Endocrinol. 2012 Jul 25;49(2):57-68.
3. Jane K. Fauser, Rino P. Donato, Joshua A. Woenig, Simon J. Proctor, Andrew P. Trotta, Phulwinder K. Grover, Gordon S. Howarth, Irmeli A. Penttila, Adrian G. Cummins. Wnt blockade with dickkopf reduces intestinal crypt fission and intestinal growth in infant rats. J Pediatr Gastroenterol Nutr. 2012 Jul;55(1):26-31.
Androgen receptor signalling, Chaperones, Microenvironment, Extracellular Matrix.
