Dr Jacques Lapointe
Position:
- Associate Professor, Department of Surgery, Division of Urology, McGill University
Credentials:
- MD at Université Laval
- PhD at Université Laval
Biography:
Dr Lapointe obtained his MD and PhD degrees from Université Laval in Québec, Canada followed by a postdoctoral training in gene expression and DNA copy number alterations profiling at Stanford University in California, USA. Dr Lapointe is currently an Associate Professor in the Department of Surgery, Division of Urology at McGill University.
The main focus of Dr Lapointe’s laboratory is prostate cancer genomics to better understand cancer biology and develop prognostic biomarkers – specifically to study gene expression and DNA copy number alteration profiles of prostate cancer using DNA microarray technology.
Their goals are to increase understanding of prostate cancer pathology, establish a new molecular classification of prostate tumours, and identify new prognostic and diagnostic markers.
Best publications:
Lapointe J, Li C, Higgins JP, Van de Rijn M, Bair E, Montgomery K, Ferrari M, Egevad L, Rayford W, Bergerheim U, Ekman P, DeMarzo AM, Tibshirani R, Botstein D, Brown PO, Brooks JD, Pollack JR. (2004) Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proceeding of National Academy of Science USA 101 : 811-816.
Lapointe J, Li C, Giacomini GC, Salari K, Huang S, Wang P, Ferrari M, Hernandez-Boussard T, Brooks JD, Pollack JR. (2007) Genomic profiling reveals distinct pathways of prostate tumorigenesis. Cancer Research, 67(8):8504-10
prostate cancer, biomarkers, gene expression, DNA copy number alterations.
