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Dr Jyotsna Batra

Dr Jyotsna Batra

Position:

  • NHMRC Early Carrer Fellow, Postdoctoral Fellow, IHBI

Credentials:

  • PhD

Websites:

Biography:

 

Dr Batra obtained her PhD in India (2008) in molecular human genetics. She received NHMRC Peter Doherty fellowship in 2011 and is currently working as Research Fellow and Group leader at the newly established Translational Research Institute.

Dr Batra has extensive experience in genetics of complex disorders, where she specialises in identification of genetic polymorphisms that predispose to prostate cancer risk and prognosis. She has contributed to large scale consortium efforts including Indian Genome Variation consortium and the largest prostate cancer consortium, PRACTICAL.

She has published in journals such as Nature Genetics, Science, and PNAS though her significant role in consortium activities.

The major focus of her group is to understand the molecular mechanism behind the genetic associations identified through various genome-wide and candidate gene association studies. 

Best publications:

  1. Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA, Ingles SA, John EM, Thibodeau SN, Schaid D, Park JY, Spurdle A, Clements J, Dickinson JL, Maier C, Vogel W, Dörk T, Rebbeck TR, Cooney KA, Cannon-Albright L, Chappuis PO, Hutter P, Zeegers M, Kaneva R, Zhang HW, Lu YJ, Foulkes WD, English DR, Leongamornlert DA, Tymrakiewicz M, Morrison J, Ardern-Jones AT, Hall AL, O'Brien LT, Wilkinson RA, Saunders EJ, Page EC, Sawyer EJ, Edwards SM, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A, Christmas T, Ogden C, Cooper CS, Southey MC, Lophatananon A, Liu JF, Kolonel LN, Le Marchand L, Wahlfors T, Tammela TL, Auvinen A, Lewis SJ, Cox A, FitzGerald LM, Koopmeiners JS, Karyadi DM, Kwon EM, Stern MC, Corral R, Joshi AD, Shahabi A, McDonnell SK, Sellers TA, Pow-Sang J, Chambers S, Aitken J, Gardiner RA, Batra J, Kedda MA, Lose F, Polanowski A, Patterson B, Serth J, Meyer A, Luedeke M, Stefflova K, Ray AM, Lange EM, Farnham J, Khan H, Slavov C, Mitkova A, Cao G; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators; PRACTICAL Consortium, Easton DF. (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet.; 41(10):1116-21.                          (IF: 30.3, Cit. 48)
  2. Batra J, Tan OL, O'Mara T, Zammit R, Nagle CM, Clements JA, Kedda MA, Spurdle AB. (2010) Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphism in ovarian cancer survival. Int J of Gynecol Cancer; 20(4):529-36.      (IF: 2.1) (IF: 3.73)
  3. Batra J, Das S, Chatterjee R, Chandra S, and Ghosh B. Monocyte chemotactic protein (MCP3) promoter polymorphism is associated with atopic asthma in the Indian population. J Allergy Clin Immunol. 2011 Mar 8. [Epub ahead of print] (IF: 9.2)
  4. Z. Kote-Jarai, A. Amin Al Olama, D. Leongamornlert, M. Tymrakiewicz, E. Saunders, M. Guy, G. Giles, G. Severi, J. Hopper,  J. Harris, J. Batra, A. Spurdle, J. Clements, F. Hamdy, D. Neal, J. Donovan, K. Muir, P.D.P. Pharoah,  S. Chanock, N. Brown, E. Castro, N. Mahmud, L. O’Brien, A. Hall1, E. Sawyer, R. Wilkinson, The UK Genetic Prostate Cancer Study Collaborators, The BAUS Section of Oncology, D.F. Easton, R. A.Eeles, Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript. Hum Genet (In press)
  5. Jyotsna Batra, Christina Nagle, Tracy O’Mara, Melanie Higgins,, Olivia L. Tan, Lene Marie Skeie, Srilakshmi Srinivasan, Felicity Lose, Kelly L. Bolton, Honglin Song, Susan J. Ramus, Simon A.Gayther, Paul D. P. Pharoah, Mary-Anne Kedda, Amanda Spurdle, Judith Clements. A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon is associated with poor ovarian cancer survival. BMC Cancer (In Press)

Kallikrein, Prostate cancer, Genetics.

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