Mr Khalid Saeed, MSc
Position:
- PhD fellow, University of Helsinki, Institute for Molecular Medicine Finland FIMM
Credentials:
- PhD fellow at Institute for Molecular Medicine Finland FIMM
Websites:
Biography:
1.3. 2010 – till date PhD student at FIMM, University of Helsinki, Finland
Ph.D. project: Finding the Achilles heel of prostate cancer by systematic RNAi and drug screening
1.10. 2009 – 28.2. 2010 Research assistant in the Department of Women's and Children's Health, Karolinska Institutet and University Hospital, Sweden.
Research Project: Study on pancreatic Dystrophy using CAR knockout gene mouse model.
1.5. 2008 – 30.9. 2009 Research assistant in the Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden.
Research Project: Recombinant Adenovirus based study to explore RNAi mechanism by controllable expression of Ago2 protein.
1.03. 2007 – 28.02. 2008 Research assistant in the Department of Pathology and Microbiology, The Aga Khan University, Karachi, Pakistan.
Research Project: pathogenic study of M.tuberculosis.
01.01.2007 - 30.06.2008 A diploma course of Certified Clinical Research Professional (CCRP) from Matrix research Centre Karachi, Pakistan
01.01.2002 – 30.04.2007 M.Sc., Biotechnology University of Karachi, Karachi, Pakistan
Best publications:
Khalid Saeed, Päivi Östling, Mari Björkman, Tuomas Mirtti , Kalle Alanen, Tiina Vesterinen, Anna Sankila,Johan Lundin, Mikael Lundin, Antti Rannikko, Stig Nordling, John-Patrick Mpindi, Pekka Kohonen, Kristiina Iljin, Olli Kallioniemi, Juha K. Rantala. Androgen receptor interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions. International Journal of Cancer, 2014, DOI: 10.1002/ijc.29303
Ning Xu, Sofia Gkountela, Khalid Saeed and Göran Akusjärvi.The 5’-end heterogeneity of adenovirus virus-associated RNAI contributes to the symmetric guide strand incorporation into the RNA-induced silencing complex. Nucleic Acids Res. 2009. Nov;37(20):6950-9. doi: 10.1093/nar/gkp764
Ex-vivo culture of human prostate cancer cells, personalized testing of drug sensitivity., RNAi mechanism., for castration-resistant prostate cancer.
