Dr Rohan Davis
Position:
- Group Leader, Griffith University, Eskitis Institute
Websites:
Biography:
I was awarded my PhD degree in organic chemistry during 2001 and have 88 publications in the fields of natural products and medicinal chemistry. During both my industry-funded (AstraZeneca, Wyeth, Actelion, Creative Antibiotics, Pfizer) and academic (Griffith University, University of Utah, The University of Melbourne) research I have been involved in the isolation and structure elucidation of over 1000 natural products from biota sources that include plants, fungi and marine invertebrates. Several of these small molecules are currently being evaluated for their potential as lead compounds, and medicinal chemistry programs have been initiated. For the past 3 years my research has been primarily focused on the identification of new anti-cancer and anti-infective agents from nature. My research group at the Eskitis Institute currently consists of 5 PhD students and 2 post-doctoral fellows.
Best publications:
1. Davis, R. A.; Carroll, A. R.; Andrews, K.; Boyle, G.; Tran, T.; Kalaitzis, J.; Healy, P. C.; Shivas, R.
Pestalactams A-C: Novel caprolactams from the endophytic fungus Pestalotiopsis sp.
Org. Biomol. Chem. 2010, 8, 1785-1790.
2. Healy, P. C.; Hocking, A.; Tran-Dinh, N.; Pitt, J. I.; Shivas, R. G.; Mitchell, J. K.; Kotiw, M.; Davis, R. A. Xanthones from a microfungus of the genus Xylaria.
Phytochemistry 2004, 65, 2373-2378.
3. Barnes, E. C.; Choomuenwai, V.; Andrews, K.; Quinn, R. J.; Davis, R. A.
Design and synthesis of screening libraries based on the muurolane natural product scaffold
Org. Biomol. Chem. 2012, 10, 4015-4023.
4. Choomuenwai, V.; Andrews, K.; Davis, R. A.
Synthesis and antimalarial evaluation of a screening library based on a tetrahydroanthraquinone natural product scaffold
Bioorg. Med. Chem. 2012, 20, 7167-7174.
5. Davis, R. A.; Longden J; Avery, V. M.; Healy, P. C.
The isolation, structure determination and cytotoxicity of the new fungal metabolite, trichodermamide C.
Bioorg. Med. Chem. Lett. 2008, 18, 2836-2839.
Natural products chemistry, Medicinal chemistry, Drug discovery, Biodiscovery, Phytochemistry, Combinatorial chemistry using natural product scaffolds.
