Dr Ruth Pidsley
Position:
- Post-doctoral researcher, Cancer Epigenetics, Garvan Institute of Medical Research
Biography:
Dr Pidsley is a postdoctoral researcher in the Cancer Epigenetics group at the Garvan Medical Research Institute, NSW. She is working on a Cancer Australia grant to investigate epigenetic variation in human prostate cancer stromal cells.
Dr Pidsley graduated from Oxford University in 2006 with a degree in Human Sciences. She then spent two years working as a research assistant in a Psychiatric Genetics laboratory at the Wellcome Trust Centre for Human Genetics, Oxford, UK.
She joined the Institute of Psychiatry at King's College London, UK in 2008, and was awarded an MSc in "Social, Genetic and Developmental Psychiatry" in 2009, and a PhD in 2013 for her thesis titled: "Profilling DNA methylation in the human brain and neuropsychiatric diseases".
Dr Pidsley recently moved to Australia to take up a postdoctoral position, which will allow her to apply the skills developed during her PhD to the study of molecular changes in the tumour microenvironment in prostate cancer.
Best publications:
Pidsley, R.,* Wong, CCY., *, Volta, M., Lunnon, K., Mill, J., Schalkwyk, L. (2013) A data-driven approach to preprocessing Illumina 450k methylation array data. BMC Genomics 14:293
Pidsley, R., Dempster, E., Troakes, C., Al-Sarraj, S., and Mill, J. (2012). Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight. Epigenetics 7, 155-163.
Davies, M.N., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, R.A., Milosavljevic. A,, Troakes, C., Al-Sarraj, S., Dobson, R., Schalkwyk, L.C., Mill, J. (2012) Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biology 13:R43.
Pidsley, R., and Mill, J. (2011). Epigenetic Studies of Psychosis: Current Findings, Methodological Approaches, and Implications for Postmortem Research. Biological Psychiatry 69, 146-156.
Dempster, E.L.*, Pidsley, R.*, Schalkwyk, L.C., Owens, S., Georgiades, A., Kane, F., Kalidindi, S., Picchioni, M., Kravariti, E., Toulopoulou, T., et al. (2011). Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet 20, 4786-4796.
Epigenetics, Methylation, Prostate cancer.
