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Dr Renea  Taylor

Dr Renea Taylor

Position:

  • Research Fellow , Prostate Cancer Research Group, Monash University, Department of Physiology

Biography:

Dr Taylor obtained her PhD from Monash University in 2003 and subsequently completed three post-doctoral training Fellowships supported by Cancer Council Victoria, US Department of Defense, and NHMRC (Peter Doherty Fellowship).

 In 2008, she was awarded a Young Investigator Grant from the Prostate Cancer Foundation of Australia to establish her own research laboratory and in 2011 she took an academic position at Monash University in the Department of Physiology where she has a combined lecturing / research position.

Her research combines stem cell biology with models of prostate cancer in order to understand disease progression. She works within a multi-disciplinary network of scientists and clinicians, using human clinical specimens that allow her to make translational observations.

Best publications:

1. Toivanen R, Frydenberg M, Murphy D, Pedersen J, Ryan A, Pook A, Berman DM, Australian Prostate Cancer BioResource, Taylor RA, Risbridger GP (2013). A pre-clinical model to identify castrate-resistant cancer repopulating cells in localized prostate tumors. Science Translational Medicine (Accepted for publication 7th May 2013)

2. Lawrence MG, Taylor RA, Toivanen R, Pedersen J, Norden S, Pook DW, Frydenberg M, Australian Prostate Cancer Bioresource, Papargiris MM, Niranjan B, Richards MG, Wang H, Collins AT, Maitland NJ, Risbridger GP (2013) A preclinical xenograft model of prostate cancer using human tumours. Nature Protocols, 8(5):836-48.

3. Toivanen R, Berman DM, Wang H, Frydenberg M, Pedersen J, Meeker AK, Ellem SJ, Risbridger GP, Taylor RA (2011) Bioassays for cancer repopulating cells. Stem Cells 29(8):1310-4.

4. McPherson SJ, Hussain S, Balanathan P, Hedwards SL, Niranjan B, Grant M, Chandrasiri UP, Toivanen R, Wang YZ, Taylor RA, Risbridger GP (2010) Estrogen receptor beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen-independent and TNFα-mediated. Proceedings of the National Academy of Sciences of the United States of America. 107(7):3123-8

5. Taylor RA, Cowin PA, Cunha GR, Trounson AO, Pedersen J, Risbridger GP (2006) Formation of human prostate tissue from embryonic stem cells. Nature Methods 3(3):179-181.

prostate cancer, xenografting, stem cells, tumour microenvironment, estrogen hormone signalling.

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