Dr Stephen McPherson
Position:
- Postdoctoral Research Fellow, Australian Prostate Cancer Research Centre - Queensland
Credentials:
- Ph.D at Monash University
- MSc at Monash University
Biography:
Dr McPherson completed a Masters Degree in 1997, investigating the role of TGF-β related growth factors in prostate cancer from Monash University.
After receiving his PhD from Monash University in 2003, he took up a position at the Monash Institute of Medical Research at Monash University, where he investigated the role of hormonal regulation in controlling the development of benign and malignant prostate disease, particularly targeting the role of estrogen and estrogenic compounds in prostatic organogenesis and development and progression of prostate cancer. This led him to the study of the roles of steroid hormone receptors, particularly estrogen receptor β, in prostate development and disease, and the interaction between stromal and epithelial cells in regulating prostate growth.
Dr McPherson joined the APCRC–Q in 2010 to initially study the relationship of AR with progesterone in the development of castrate resistance in prostate cancer and the roles of other nuclear hormone receptors including Estrogen receptor, in prostate cancer. His research interests include: changing expression of nuclear hormone receptors in prostate disease, prostatic response to the changing hormonal environment, aging and progression of prostate cancer, and the role of ERβ in prostate growth and disease. He also has an ongoing interest in the roles of activin and follistatin in prostate cancer and the characterisation of novel compounds as AR and ER receptor-targeted therapeutics.
Estrogen Receptor, Androgen Receptor, Activin, Nuclear Receptors, Therapeutic compounds.
